Tue, 25 Jul 2023 08:20:36 +0000Latest news in proactive ageing/article/6-ways-combat-ageismTue, 25 Jul 2023 08:20:36 +0000/article/6-ways-combat-ageismDespite a widespread and outdated view of older people, and an abundance of stereotypes, awareness of what is known as ageism is limited. A new short guide gives tips for how you can use your communication to counter discrimination against older people./article/causes-osteoarthritis-mapped-new-biobankTue, 25 Jul 2023 07:59:00 +0000/article/causes-osteoarthritis-mapped-new-biobankThrough molecular studies of knee tissue and advanced synchrotron radiation imaging techniques, researchers hope to gain new insights into the early development of osteoarthritis. The hope is to pave the way for new treatments./article/researchers-time-new-approach-ageingTue, 25 Jul 2023 07:45:44 +0000/article/researchers-time-new-approach-ageingWe usually associate ageing with a shrinking life span, sickness and death. The difficulty of imagining ourselves as old means that we go to great lengths to avoid planning for later life. Yet researchers argue that we have everything to gain by looking at life as a journey where preparations for the future provide opportunities for living a full life – until it really is over./article/we-are-getting-older-and-heavier-osteoarthritis-increasingThu, 15 Jun 2023 10:58:02 +0000/article/we-are-getting-older-and-heavier-osteoarthritis-increasingThe number of patients with osteoarthritis has increased dramatically since the 1950s. Along with diabetes, the illness is now one of the fastest-growing endemic diseases in the world. Andrea Dell’Isola, an associate professor at the Department of Clinical Sciences at �۶���Ƶ in Sweden, investigating the connection between osteoarthritis and metabolic diseases in a new research project./article/new-study-questions-efficacy-many-osteoarthritis-treatmentsWed, 26 Apr 2023 10:04:42 +0000/article/new-study-questions-efficacy-many-osteoarthritis-treatmentsRecruiting osteoarthritis patients with a lot of pain to clinical studies, may give incorrect results if the researcher does account for the natural variation in pain that occurs. A research group from �۶���Ƶ in Sweden is now drawing attention to the traps in clinical studies on osteoarthritis./article/triple-success-prestigious-eu-grant-roundThu, 30 Mar 2023 10:47:05 +0000/article/triple-success-prestigious-eu-grant-roundThree researchers at �۶���Ƶ in Sweden, all with a long list of significant research credentials, have been awarded the ERC Advanced Grant worth EUR 2.5 million each to further develop and advance their research projects. This concerns research on a fundamentally changed food system, chaperone proteins’ function in neurodegenerative diseases, and blood tests for rapid screening of drugs in the treatment of Alzheimer’s disease./article/brains-immune-cells-can-be-triggered-slow-down-alzheimers-diseaseTue, 29 Nov 2022 13:16:53 +0000/article/brains-immune-cells-can-be-triggered-slow-down-alzheimers-diseaseThe brain's big-eating immune cells can slow down the progression of Alzheimer's disease. This is shown by a study that is now published in Nature Aging. /article/alzheimers-disease-can-be-diagnosed-symptoms-emergeFri, 11 Nov 2022 11:44:37 +0000/article/alzheimers-disease-can-be-diagnosed-symptoms-emergeA large study led by �۶���Ƶ in Sweden has shown that people with Alzheimer's disease can now be identified before they experience any symptoms. It is now also possible to predict who will deteriorate within the next few years. The study is published in Nature Medicine, and is very timely in light of the recent development of new drugs for Alzheimer's disease./article/blood-test-detects-alzheimers-people-down-syndromeWed, 24 Aug 2022 11:29:09 +0000/article/blood-test-detects-alzheimers-people-down-syndromeAround 80% of people with Down syndrome develop Alzheimer’s disease, often when they are between 40 and 50 years old. A study led by �۶���Ƶ in Sweden has shown that a simple blood test can detect Alzheimer’s disease in people with Down syndrome with a high degree of certainty. The findings are important for several reasons, not least the ability to make a correct diagnosis without invasive procedures. The study was recently published in JAMA Neurology./article/psychiatric-symptoms-alzheimers-diseaseTue, 19 Apr 2022 10:40:10 +0000/article/psychiatric-symptoms-alzheimers-diseaseIn addition to memory problems and other cognitive symptoms, most people with Alzheimer’s disease also suffer from mental health issues. It has long been unclear whether these occur because of tissue changes in the brain, or whether they represent psychological reactions to cognitive symptoms. A study from �۶���Ƶ in Sweden has provided new insight, and is published in Biological Psychiatry. /article/simple-diagnostic-tool-predicts-individual-risk-alzheimersMon, 24 May 2021 18:39:04 +0000/article/simple-diagnostic-tool-predicts-individual-risk-alzheimersResearchers at �۶���Ƶ in Sweden have developed an algorithm that combines data from a simple blood test and brief memory tests, to predict with great accuracy who will develop Alzheimer's disease in the future. The findings are published in Nature Medicine./article/alzheimers-disease-composed-four-distinct-subtypesThu, 29 Apr 2021 15:48:09 +0000/article/alzheimers-disease-composed-four-distinct-subtypesAlzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can now show how tau spreads according to four distinct patterns that lead to different symptoms with different prognoses of the affected individuals. The study was published in Nature Medicine./article/women-accumulate-alzheimers-related-protein-fasterThu, 25 Mar 2021 15:29:29 +0000/article/women-accumulate-alzheimers-related-protein-fasterAlzheimer’s disease seems to progress faster in women than in men. The protein tau accumulates at a higher rate in women, according to research from �۶���Ƶ in Sweden. The study was recently published in Brain. /article/app-predicts-risk-developing-alzheimersMon, 30 Nov 2020 17:15:52 +0000/article/app-predicts-risk-developing-alzheimersA new study from �۶���Ƶ in Sweden shows that validated biomarkers can reveal an individual’s risk of developing Alzheimer’s disease. Using a model that combines the levels of two specific proteins in the blood of those with mild memory impairment, the researchers are able to predict the risk of developing Alzheimer’s. The researchers have also developed an app that doctors can use to give patients a risk assessment./article/new-type-blood-test-gives-more-reliable-diagnosis-alzheimers-diseaseThu, 22 Oct 2020 10:20:36 +0000/article/new-type-blood-test-gives-more-reliable-diagnosis-alzheimers-diseaseA simple blood test with 90% accuracy that shows whether a patient has Alzheimer’s disease has floored the research community, which is calling it a gamechanger. Oskar Hansson, professor of neurology at �۶���Ƶ and Skåne University Hospital, is leading the research team that has rapidly taken a major step towards better diagnostics. “The blood test will make it easier for general practitioners all over the world to make better diagnoses. It feels very satisfying”, says Oskar Hansson. /article/new-blood-test-shows-great-promise-diagnosis-alzheimers-diseaseTue, 28 Jul 2020 16:59:38 +0000/article/new-blood-test-shows-great-promise-diagnosis-alzheimers-diseaseA new blood test demonstrated remarkable promise in discriminating between persons with and without Alzheimer’s disease and in persons at known genetic risk may be able to detect the disease as early as 20 years before the onset of cognitive impairment, according to a large international study published today in the Journal of the American Medical Association (JAMA) and simultaneously presented at the Alzheimer’s Association International Conference./article/how-toxic-protein-spreads-alzheimers-diseaseFri, 29 May 2020 10:42:44 +0000/article/how-toxic-protein-spreads-alzheimers-diseaseToxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer’s disease. A new study published in Nature Communications shows that the spread of toxic tau in the human brain in elderly individuals may occur via connected neurons. The researchers could see that beta-amyloid facilitates the spread of toxic tau. /article/blood-test-enables-early-diagnosis-alzheimers-disease-0Mon, 02 Mar 2020 17:51:22 +0000/article/blood-test-enables-early-diagnosis-alzheimers-disease-0Diagnosing Alzheimer's disease is often difficult, as several other conditions can cause similar symptoms. Researchers at �۶���Ƶ in Sweden have now discovered a blood marker that can accurately diagnose Alzheimer’s in the early stages of the disease./article/blood-test-enables-early-diagnosis-alzheimers-diseaseMon, 02 Mar 2020 17:51:20 +0000/article/blood-test-enables-early-diagnosis-alzheimers-diseaseDiagnosing Alzheimer's disease is often difficult, as several other conditions can cause similar symptoms. Researchers at �۶���Ƶ in Sweden have now discovered a blood marker that can accurately diagnose Alzheimer’s in the early stages of the disease./article/skiers-had-lower-incidence-depression-and-vascular-dementia-not-alzheimersTue, 26 Nov 2019 11:56:40 +0000/article/skiers-had-lower-incidence-depression-and-vascular-dementia-not-alzheimersHalf as many diagnosed with depression, a delayed manifestation of Parkinson’s, a reduced risk of developing vascular dementia - but not Alzheimer’s. These connections were discovered by researchers when they compared 200 000 people who had participated in a long-distance cross-country ski race between 1989 and 2010 with a matched cohort of the general population. The results of the population register study, led by researchers at �۶���Ƶ in Sweden together with Uppsala University, were recently published in three scientific articles. /article/osteoarthritis-linked-higher-risk-dying-cardiovascular-diseaseTue, 16 Jul 2019 10:18:24 +0000/article/osteoarthritis-linked-higher-risk-dying-cardiovascular-diseaseResearchers at �۶���Ƶ in Sweden have investigated the link between osteoarthritis and mortality in an epidemiological study. It was shown that the risk of dying from cardiovascular disease was higher for people with osteoarthritis than for the rest of the population. /article/high-rates-opioid-prescriptions-osteoarthritisMon, 08 Jul 2019 08:42:47 +0000/article/high-rates-opioid-prescriptions-osteoarthritisOpioids work against severe pain but the risks of side effects and addiction are high. In the USA alone, 26 people die every day from overdoses. Now researchers in an international collaboration have investigated how common opioid prescriptions are for osteoarthritis patients in Sweden. It emerged that every fourth patient was prescribed opioids at some point between November 2014 and October 2015. /article/new-blood-test-detecting-alzheimers-diseaseTue, 25 Jun 2019 10:52:37 +0000/article/new-blood-test-detecting-alzheimers-diseaseResearchers from �۶���Ƶ, together with the Roche pharmaceutical company, have used a method to develop a new blood marker capable of detecting whether or not a person has Alzheimer’s disease. If the method is approved for clinical use, the researchers hope eventually to see it used as a diagnostic tool in primary healthcare. This autumn, they will start a trial in primary healthcare to test the technique./article/new-method-enables-accurate-diagnosis-alzheimers-diseaseWed, 19 Sep 2018 10:15:50 +0000/article/new-method-enables-accurate-diagnosis-alzheimers-diseaseDiagnosing Alzheimer's disease can be difficult, as several other conditions can cause similar symptoms. Now a new brain imaging method can show the spread of specific tau protein depositions, which are unique to cases with Alzheimer's. ‟The method works very well. I believe it will be applied clinically all over the world in only a few years”, says Oskar Hansson. Hansson is a professor of clinical memory research at �۶���Ƶ in Sweden who has led a major international study on the new method. /article/living-parkinsons-challenge-everyday-lifeWed, 22 Aug 2018 22:00:00 +0000/article/living-parkinsons-challenge-everyday-lifeParkinson’s disease, a condition whose complications worsen as the years go by, can mean that getting older becomes particularly challenging. How can life be made easier for these individuals, so that they can continue to be active and participate in society? This is the aim of a multi-year study that examines the interplay between health and home among people ageing with Parkinson’s disease./article/pursuit-early-signs-alzheimers-diseaseThu, 22 Feb 2018 23:00:00 +0000/article/pursuit-early-signs-alzheimers-diseaseWhen everyday life is not recognisable, when conversation is silenced, when memories disappear. Alzheimer’s disease is contracted by 60 000 people in Sweden annually and accounts for 60 per cent of all types of dementia disease. There is no cure, but research has come a long way in diagnosing the disease at an early stage. “Over the past ten years there has been a revolution concerning our possibilities to make reliable diagnoses. Using modern methods, we can show if a person actually has the pathologies in the brain that cause Alzheimer’s”, says the neurologist Oskar Hansson, one of Sweden’s leading researchers on Alzheimer’s disease./article/prestigious-erc-grants-awarded-lund-researchersThu, 30 Nov 2017 15:06:56 +0000/article/prestigious-erc-grants-awarded-lund-researchersCapsules for transporting drugs, knee injuries that are really osteoarthritis, skin cells reprogrammed into nerve cells, variations in our DNA affecting the production of blood cells, and the urban sharing economy as a potential solution to our sustainability challenges. These are the research areas which have been awarded ERC Consolidator Grants from the European Research Council (ERC) in the 2017 round of awards.